(Ranunculaceae Juss.) afforded a dilactone, anemonin (1) isolated, purified and identified by spectroscopic methods and comparison of their spectral data with the reported data.
Key Words: Anemonin; Pulsatilla wallichiana; Physochlaina praealta; Bioassays; Gilgit-Baltistan.
Because of the investigation, a dilactone namely anemonin (1) was isolated and identified for the first time from P.
Phytochemical investigation of Pulsatilla wallichiana resulted in the isolation of anemonin (1) and its structure was determined by means of 1D and 2D NMR spectra (Figure 1).
wallichiana exhibited 42.6% inhibition at a concentration 25 mg/ml in antiinflammatory activity and anemonin, a small natural product, was isolated from P.
was investigated to isolate the bioactive constituents and as a result anemonin (1) was isolated and identified for the first time from P.
Wang, Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor, J.
Du, Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL-1beta/NF-kappaB pathway, J.
PR is traditional Korean herbal medicine prepared from the roots of Pulsatilla koreana Nakai and contains several phytochemicals, including anemonin
, hederagenin, oleanolic acid, and deoxypodophyllotoxin [14, 15].