Duchenne's muscular dystrophy

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Related to Duchenne's muscular dystrophy: Becker muscular dystrophy

Du·chenne's muscular dystrophy

The most common form of muscular dystrophy, caused by a genetic mutation resulting in the absence of the structural protein dystrophin, in which fat and fibrous tissue infiltrate muscle tissue and cause eventual weakening of the respiratory muscles and the myocardium. The disease, which almost exclusively affects males, begins in early childhood and usually causes death before adulthood.

[After Guillaume B.A. Duchenne, (1806-1875), French physician.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Duchenne's muscular dystrophy - the most common form of muscular dystrophy; inheritance is X-linked recessive (carried by females but affecting only males)
dystrophy, muscular dystrophy - any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Griggs et al., "Randomized, double-blind six-month trial of prednisone in Duchenne's muscular dystrophy," New England Journal of Medicine, vol.
Cardiomyopathy and pulmonary emboli in terminal Duchenne's muscular dystrophy. Am Heart J 1990;119:690-3.
A controversial scientific report claims that a new type of cell therapy boosts the muscle strength of boys suffering from Duchenne's muscular dystrophy, the most severe form of this muscle-wasting disease.

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