nedocromil

(redirected from Tilade)
Also found in: Medical.

ne·doc·ro·mil

 (nə-dŏk′rə-mĭl′)
n.
An anti-inflammatory drug, C19H15N, used in an inhaler in the form of a sodium salt to treat mild-to-moderate asthma.

[ne- (perhaps from 9-ethyl, beginning of the chemical name, referring to the presence of an ethyl group in ninth position) + d(i)- + o(xy)- + shortening and alteration of cromolyn.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
If these cognitive symptoms bother you, speak to your health care provider, who may adjust dosage levels or suggest alternative drugs such as leukotriene modifiers (Singulair; Zyflo), mast cell stabilizers (Crolom; Nasalcrom; Tilade), or the antibody omalizumab (Xolair), which prevents the release of inflammatory chemicals that narrow the airways.
The chlorofluorocarbon (CFC) version of Tilade (nedocromil) was removed from market June 14, 2010 and Intal (cromolyn sodium) will be removed December 31, 2010.
He or she may recommend adjusting dosage levels or replacing corticosteroid therapy with alternative drugs such as leukotriene modifiers (Singulair; Zyflo), mast cell stabilizers (Crolom; Nasalcrom; Tilade), or the antibody Omalizumab (Xolair), which prevents the release of inflammatory chemicals that narrow the airways.
Another mast cell stabilizer frequently used to help control allergies is nedocromil (Tilade Inhaler).
Cromolyn (Intal), nedocromil (Tilade) and corticosteroids are examples of anti-inflammatory medications currently available to treat asthma.
The study was designed to assess the safety and efficacy of inhaled budesonide (Pulmicort), compared with treatment with nedocromil (Tilade) or placebo.
The seven MDI drugs include: flunisolide (Forest's Aerobid), triamcinolone (Kos' Azmacort), metaproterenol (Boehringer Ingelheim's Alupent), pirbuterol (3M's Maxair), cromolyn (King's Intal), nedocromil (King's Tilade) and the combination of albuterol and ipratropium (Boehringer's Combivent).
Another systematic review of 20 RCTs (15 studying children and 5 studying adults) with patients aged >6 years showed that 4 mg of nedocromil (Tilade) inhaled 15 to 60 minutes before exercise significantly reduced the severity and duration of exercise-induced bronchoconstriction compared with placebo.