Lim, "Co-culture of stromal and erythroleukemia
cells in a perfused hollow fiber bioreactor system as an in vitro bone marrow model for myeloid leukemia," Biotechnology and Bioengineering, vol.
Thus, in vitro assays showed that activated NK cells from aMCI and mAD patients lyse K562 cells, an erythroleukemia
cell line .
The human erythroleukemia
cell line K562 was purchased from ATCC and used as a control target for NK cell functional assays.
Thus, for example, diosgenin has antiproliferativeactivity, namely, inprostatecancer(PC-3 and DU-145 cells) , colon carcinoma (HCT-116 and HT-29 cells) , erythroleukemia
(HEL cells) , squamous carcinoma (A431, Hep2, and RPMI2650 cells) , hepatocellular carcinoma (HepG2 and HCC cells) [6,25,29], gastric cancer (BGC-823 cells) , lung cancer (A549 cells) , breast cancer (MCF-7) [6,32-34], and human chronic myeloid leukemia (CML) (K562 cells) .
cells line was grown is suspension in RPMI 1640 media (Cultilab, Campinas, Sao Paulo, Brazil) supplemented with 10% fetal bovine serum (FBS; Cultilab), 100 U/mL of penicillin, and 100 [micro]g/mL of streptomycin in a humidified atmosphere at 37[degrees]C in 5% C[O.sub.2].
Wong, "Prostacyclin receptor induces STAT1 and STAT3 phosphorylations in human erythroleukemia
cells: a mechanism requiring PTX-insensitive G proteins, ERK and JNK," Cellular Signalling, vol.
Amini et al., "Two COX-2 inhibitors induce apoptosis in human erythroleukemia
K562cells by modulating NF-[kappa]B and FHC pathways," DARU, Journal of Pharmaceutical Sciences, vol.
Moreover, diosgenin induces megakaryocytic differentiation of human erythroleukemia
cells through ERK and sonic hedgehog pathway activation (Fernandez-Zapico et al.
Reductions in gamma-globin mRNA levels restricted to the cytoplasm of 5-fluorouridine treated K-562 human erythroleukemia
Leukemia, refers to white blood cell malignancies with the exception for erythroleukemia
(AML-M6) which arises from precursors of RBCs.
The first, also called erythroleukemia
, involves myeloblasts and rubriblasts (BENNETT et al., 1976).
nucifera (typical A variety, commonly known as "olho-de-cravo", and the common variety) were tested on human erythroleukemia
cell line K562 and Lucena 1, a multidrug-resistant (MDR) and vincristine-resistant derivative of K562.