homeobox gene


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Related to homeobox gene: Hox gene

homeobox gene

n.
Any of a large family of genes containing a characteristic sequence of nucleotides, called the "homeobox," that codes for an amino acid sequence that binds to DNA. Homeobox genes are found in all multicellular organisms and play an important role in embryologic development.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ho′me•o•box gene`

(ˈhoʊ mi əˌbɒks)
n.
any of a group of genes whose function is to divide the early embryo into bands of cells with the potential to become specific organs or tissues.
[1985–90; homeo- + box1]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.homeobox gene - one of various similar homeotic genes that are involved in bodily segmentation during embryonic development
homeotic gene - one the genes that are involved in embryologic development
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References in periodicals archive ?
The transcriptional coactivator Eya1 and the homeobox gene Six1 are believed to participate in the early differentiation of hair cells and neurons (10), which are in turn regulated by Foxil (11).
The homeobox gene caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia.
Keywords: Congenital, Homeobox gene, Hypodontia, Missense mutation, MSX1 gene.
Anti-mucin MGGMC-1 (clone: HIK1083), special AT-rich sequence-binding protein 2 (SATB2), caudal-related homeobox gene 2 (CDX2), and androgen receptor consistently show negativity.
Analysis of the genes PAX6 (11p13), PITX2 (or RIEG1) (4p25-26), PITX3 (RIEG/PITX homeobox gene family) (10q25), CYP1B1 (cytochrome P4501B1 gene) (2p22), FKHL7 (Forkhead transcription factor) and B3GALTL gene (13q12.3) revealed no deletions or duplications in these genes.
Homeobox gene expression in adult dorsal root ganglia during sciatic nerve regeneration: is regeneration a recapitulation of development?
To the Editor: Iroquois-related Homeobox 3 (IRX3) is a member of the Iroquois homeobox gene family that encodes a protein known for its essential role in spinal cord development.[1] Recent studies reported that the expression level of this gene in hypothalamus is related to calorie intake and body composition.[1],[2] There are some evidences that polymorphisms of IRX3 gene and the level of IRX3 gene expression are both related to obesity through various mechanisms.
Homeobox gene DLX4 expression is increased in idiopathic human fetal growth restriction.
Konturek, "Bile acids induce overexpression of homeobox gene CDX2 and vascular endothelial growth factor (VEGF) in human Barrett's esophageal mucosa and adenocarcinoma cell line," Scandinavian Journal of Gastroenterology, vol.
Gudas, "Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice," Developmental Dynamics, vol.
The abnormal expression of homeobox gene HOXA is implicated in the development of acute leukemia in childhood [10].