In extreme cases, almost half of all the proteins that were built, used a different reading frame
or code than the expected code.
Maximum-likelihood phylogeny of the concatenated open reading frame
1 and 2 nucleotide sequences of hare hepatitis E virus (HEV) strain from Germany (black diamond), related strains from rabbits (bold) and humans, and reference Orthohepevirus A strains, as defined by Smith et al.
(BCP = basal core promoter; Pre-C = pre-core; ORF = open reading frame
; PC = pre-core-core; s Ag = surface antigen; nt = nucleotide; aa = amino acid.
PRRSV replication can be significantly suppressed by interrupting formation of the open reading frame
7 (ORF7) gene and organizing nucleocapsid protein N [12-14].
Upon further investigation, the team found that a tumor-suppressor gene, called alternative reading frame
(ARF), which is normally suppressed in mouse and human iPSCs, remained active in the mole rat iPSCs.
Primers were designed to generate a product of easily sequenced length (around 650 bases) and be within the open reading frame
of each locus greater than 100 base pairs from each end.
An intact LINE-1 sequence measures approximately 6 kb in length and encodes 2 well-recognized proteins, open reading frame
1 protein (ORF1p) and ORF2p (Fig.
In this paper, we developed an alignment-free tool, named as "Lncident" (LncRNAs identification), to rapidly predict lncRNA and messenger RNA (mRNA) utilizing sequence intrinsic composition features and open reading frame
information based on support vector machine (SVM).
abortus BAB1 0279 open reading frame
(ORF) of genomic island 3 (GI-3).
The research also indicated how these non-random results can be harnessed to produce a desired effect, such as a gene knockout or the reading frame
restoration of a disease-causing allele.
Scientists have identified a mutation in a gene called "chromosome 9 open reading frame
72" or C9ORF72.