This involvement is likened to the appearance of a tiger skin (tigroid
Clinically, the patients have a marked susceptibility to acute sunburns after minimum exposure, facial freckling, increased risk of skin cancer and pigmentary changes that are characteristic of XP.4 The neurological and somatic features are CS-like3 and include growth failure, intellectual disability, delayed development, sensorineural hearing deficit, progeria, failure to thrive, and severe cachexia characterized by deep-set eyes.4 The neuroimaging reveals brain atrophy, ventriculomegaly, tigroid
demyelination and microcephaly, findings also characteristic of CS.1,4 Here, we report a case of a 3-year-old girl presenting with clinical features strongly suggestive of XP-CS complex.
Although clinical manifestations are heterogeneous (5,6), the most relevant neurological signs are nystagmus, developmental delay, spasticity, along with neuroimaging supporting aberrant myelination of the Central Nervous System (CNS) compromising primarily the periventricular white matter, with a tigroid
striation pattern that responds to the conservation of myelinated islets, and also an alteration of the N-acetyl aspartate and choline profiles on the brain magnetic resonance spectroscopy (5,7).
There is less pigment in the peripheral retina of healthy eyes, resulting in the commonly seen tigroid
fundus appearance (see Figure 5A); this appearance is typically accentuated in eyes with depigmentation, such as in high myopia or retinal atrophy.
Fundus examination with 90-D lens revealed peripapillary atrophy and peripheral tigroid
fundus in both eyes.
heart (necrotizing myocarditis) and acute gastroenteritis which are more dangerous and lead to acute mortality (OIE, 2012; McGavin and Zachary, 2012).This virus can lead to endocrine damage in recovered animals so led to rough coat with long hairs and thereby thermoregulation is affected.
However, the ability to detect glaucoma, especially by clinicians lacking expertise in glaucoma, has been hindered by the poor quality of C-DP images (e.g., light exposure, poor contrast, and color tone), which are frequently found in media opacity and tigroid
fundus cases .
Fine needle aspiration from lump showed dispersed tumor cells with round nucleus, large prominent nucleoli, and vacuolated cytoplasm in tigroid
Imaging features are pathognomonic, consisting of the well-described tigroid
or folial appearance of alternating superficial bands of hyper- and hypointensity on Tl and T2 weighted imaging within the cerebellar lesion.
Some breeds (Lhasa Apso, Spitz) with less pigmented non tapetal fundus, in which choroidal blood vessels were visible, had a tigroid
or striped pattern.
1), diffuse infiltration of the bowel and a 'tigroid
' enhancement pattern of both kidneys as well as mesenteric metastases (Fig.
Included in this group are a passionate Bard, a Lemurian thief, a priest, a shape shifter, a black Tigroid
talking cat, a princess, a holy knight, and a shape shifter.